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class="uk-width-1-1"><div class="uk-panel"> <article><p><span style="color: #335399; font-family: helvetica; font-size: 24pt;"><strong><span mce-data-marked="1"><span mce-data-marked="1"> </span></span></strong> </span></p></article><section><p>Tadalafil is a medication available only by prescription, designed to address erectile dysfunction in men. It is a cost-effective alternative to the branded version known as Cialis.</p> <h2>Using tadalafil</h2> <p>To use tadalafil effectively, take a tablet of 10mg or 20mg at least 30 minutes prior to sexual activity. The effects of the medication can last up to 36 hours. For those who require regular treatment more than twice a week, a low daily dose of 2.5mg or 5mg is recommended. Be sure to read the patient information leaflet for a comprehensive list of potential side effects, precautions, and interactions with other medications.</p> <h2>Who can benefit from tadalafil?</h2> <p>Tadalafil is intended for adult men who have been diagnosed with erectile dysfunction, which is the inability to achieve or maintain an erection sufficient for sexual activity. Clinical studies have demonstrated that tadalafil significantly enhances the ability to obtain a firm erection suitable for sexual intercourse.</p> <h2>Mechanism of action</h2> <p>Tadalafil operates similarly to other medications for erectile dysfunction, such as Viagra (sildenafil), Levitra (vardenafil), and Spedra (avanafil). It works by facilitating the relaxation of blood vessels in the penis, thereby enhancing blood flow during sexual stimulation. This effect is achieved by inhibiting the PDE5 enzyme, making these medications known as PDE5 inhibitors. They have minimal impact on other parts of the body.</p> <h2>The 'weekend pill'</h2> <p>Tadalafil is often referred to as the 'weekend pill' due to its extended duration of action, which can span up to 36 hours. This prolonged efficacy, compared to the shorter durations of other medications like Viagra (4 hours) and Levitra (4-5 hours), has contributed to its growing popularity.</p> <h2>How to use tadalafil for erectile dysfunction</h2> <p>Tadalafil tablets are available in four dosages: 2.5mg, 5mg, 10mg, and 20mg. Most men opt for a 10mg or 20mg tablet as needed. The lower doses are intended for daily use, although some men may find that an occasional 5mg tablet suffices. It is not advisable to take the 20mg dose on a regular daily basis.</p> <h2>Initial use of tadalafil</h2> <p>The typical starting dose is a single 10mg tablet taken at least 30 minutes before sexual activity. The tablet should be swallowed whole with water and can be taken with or without food. Sexual stimulation is necessary for tadalafil to be effective. Before increasing the dose, it is recommended to try the medication several times at the current dose level. Tadalafil should not be taken simultaneously with or within 24 hours of other oral erectile dysfunction treatments.</p> <h2>As-needed dosage (10mg, 20mg)</h2> <p>Most men take tadalafil as needed, at least 30 minutes before anticipated sexual activity. A single tablet of 10mg or 20mg remains active for up to 36 hours. The maximum dose is 20mg within a 24-hour period, and continuous daily use of these doses is not recommended.</p> <h2>Continuous daily dosage (2.5mg, 5mg)</h2> <p>Men who require regular treatment twice a week or more may prefer a low-dose tablet of 2.5mg or 5mg every day. Tadalafil is the only erectile dysfunction medication with a low-dose daily regimen. The recommended dose is 5mg once a day at approximately the same time. The dose may be reduced to 2.5mg based on individual tolerance. These low-dose tablets provide continuous treatment, although it may take several days to reach an effective dose. Men should consult their doctors before starting daily treatment.</p> <h2>Effectiveness of tadalafil</h2> <p>Clinical studies have shown that tadalafil significantly improves erectile dysfunction and the ability to have successful sexual intercourse. The medication is effective across different severity levels of erectile dysfunction, with improvement rates of 86% for mild, 83% for moderate, and 72% for severe cases. No dose adjustments are recommended for elderly or diabetic patients. However, the effectiveness of tadalafil in patients who have undergone pelvic surgery or prostate gland removal is not known.</p> <h2>Who should avoid tadalafil</h2> <p>All men with erectile dysfunction should consult a doctor in person before obtaining the medication online. While online consultations can check for contraindications and interactions with other medicines, they do not replace an initial consultation and diagnosis with your regular doctor, where a physical examination and tests can be carried out.</p> <h2>Warnings and precautions</h2> <p>Sexual activity can pose a risk to patients with heart disease due to the extra strain it puts on the heart. Do not take tadalafil if you have severe heart disease or have had a heart attack within the last 90 days, or a stroke within the last 6 months. If you suffer from hypotension or uncontrolled hypertension, take note. Also, if you've ever experienced vision loss due to non-arteritic anterior ischemic optic neuropathy (NAION), commonly referred to as a "stroke of the eye," it's crucial to exercise caution.</p> <h3>Before taking tadalafil, individuals with the following conditions should consult their healthcare provider:</h3><ul><li> Sickle cell anemia, a disorder affecting red blood cells.</li><li> Multiple myeloma, a type of bone marrow cancer.</li><li> Leukemia, cancer of the blood cells.</li><li> Any penile deformity.</li><li> Severe liver or kidney issues.</li></ul><h2>Tadalafil and other medications</h2> <p>Concomitant use of tadalafil with certain medications is contraindicated:</p><ul><li> Within 24 hours of using Viagra (sildenafil), Levitra (vardenafil), or Spedra (avanafil).</li><li> Antiviral drugs such as indinavir and ritonavir for HIV treatment.</li><li> Antifungal agents like itraconazole or ketoconazole.</li><li> Nitrates for angina, including isosorbide mononitrate, isosorbide dinitrate, nicorandil, and glyceryl trinitrate, as serious reactions may occur.</li><li> Recreational drugs such as amyl nitrate ("poppers"), which can cause serious reactions.</li><li> Alphablockers used to treat high blood pressure or prostate enlargement, including doxazosin, prazosin, alfuzosin, terazosin, indoramin, and tamsulosin.</li><li> Antibiotics such as erythromycin, clarithromycin, or rifampicin.</li><li> Anticonvulsants like phenobarbital, phenytoin, or carbamazepine.</li></ul><p>If you have any doubts, please contact our doctors or consult your healthcare provider before ordering tadalafil online.</p> <h2>Other precautions</h2><ul><li> Alcohol and grapefruit juice may interfere with tadalafil's effectiveness.</li><li> Some men may experience a reduction in sperm count, although this is unlikely to affect fertility.</li><li> Dizziness has been reported in some men taking tadalafil during clinical studies. Exercise caution when driving or operating machinery.</li><li> Tadalafil may contain lactose and trace amounts of sodium.</li><li> For individuals with severe renal impairment, the maximum recommended dose is 10 mg, and daily dosing is not advised.</li><li> Tadalafil is not intended for use by individuals under 18 or women. Keep all medications out of the reach of children.</li></ul><h2>Potential side effects of tadalafil</h2> <p>Significant side effects are rare, but they are more likely with higher doses. The minimum effective dose is recommended.</p> <p>The most common side effect is a bluish or yellowish tinge to vision, which is harmless and temporary. Similar visual changes can occur with other erectile dysfunction treatments.</p> <p>Other common side effects (affecting 1%-10%) include headache, back pain, muscle aches, pain in the arms or legs, nasal congestion, facial flushing, and indigestion.</p> <p>A very rare but serious side effect is priapism, a prolonged and painful erection lasting several hours. Priapism can result in permanent penile damage and requires immediate medical attention in an emergency department.</p> <p>The patient information leaflet included with the medication provides a comprehensive list of side effects.</p> <h2>Alternative treatments</h2> <p>Not all men require a medication that lasts up to 36 hours. Other oral PDE5 inhibitors include Viagra (sildenafil), Levitra (vardenafil), and Spedra (avanafil), which typically have a duration of 4 hours.</p> <p>Other treatments for erectile dysfunction include topical applications, penile injections, and surgical devices. Counseling may be beneficial if psychological factors contribute to ED. Lifestyle modifications, such as improving diet and adopting healthier habits, can also be helpful.</p> <p>Tadalafil is also used to treat benign prostatic hyperplasia (enlarged prostate) symptoms and, under specialist supervision, in higher doses for pulmonary hypertension.</p> <h2>Generic tadalafil vs. branded Cialis</h2> <p>Generic tadalafil became legally available in the US in November 2017 after the exclusive license for branded Cialis held by Lilly expired. Cialis is the brand name used by Lilly for its version of tadalafil. Both contain the same active ingredient and have identical medical effects.</p> <p>Prior to the expiration of the exclusive license, only Lilly was permitted to sell tadalafil legally in the UK. Afterward, other pharmaceutical companies could legally supply generic tadalafil, leading to lower prices.</p> <p>Dr. Fox may supply any US-licensed brand of tadalafil (Accord, Aspire, Bristol Labs, Cipla, Clydesdale, Crescent, Kosei, Medreich, Mercury, Milpharm, Mylan, Noumed, Strides Pharma, Sovereign, Sun, Teva). Patients can request a preferred brand after placing an order.</p> <h3>Generic medications are medically equivalent to branded originals and are usually more affordable. Erectile dysfunction: understanding the underlying factors</h3> <p>Erectile dysfunction (ED) is a widespread health issue, impacting a significant proportion of men, with estimates suggesting that up to 40% of men experience it by the time they reach the age of fifty. It is crucial to note that many men who encounter ED are generally in good health, although it can sometimes indicate underlying health problems such as impaired blood flow and arterial narrowing.</p> <p>A variety of medical conditions can contribute to the development of erectile dysfunction. These include diabetes, elevated cholesterol levels, low testosterone levels, abnormal thyroid hormone levels (both too low and too high), obesity, and poor blood circulation. Notably, ED can also be linked to cardiovascular disease and cerebrovascular accidents, commonly known as strokes. Addressing and managing these underlying health issues can lead to an improvement in symptoms and help prevent related diseases.</p> <p>Psychological factors and lifestyle choices can also play a role in the onset of erectile dysfunction. Stress, psychosexual issues, smoking, excessive alcohol consumption, obesity, and a lack of physical activity can all contribute to the development of ED. In many cases, symptoms may improve when these factors are effectively managed. Additionally, other potential causes may include spinal injuries or surgical procedures involving the prostate or bowel. Even engaging in regular cycling for prolonged periods, such as three or more hours daily, may contribute to the development of erectile dysfunction.</p> <p>Given the potential complexity and seriousness of the issue, it is highly advisable to seek a face-to-face consultation with a general practitioner (GP). This is particularly important if the erectile dysfunction has recently emerged or is progressively worsening. During the consultation, the GP will conduct a thorough assessment, which may include performing relevant tests and providing tailored advice to address the issue effectively.</p></section></div></div> </section> </div> <aside class="tm-sidebar-b uk-width-medium-1-4"><div class="uk-panel"><h3 class="uk-panel-title">Contact Us</h3> <div class="addthis_toolbox addthis_32x32_style addthis_default_style"><a class="addthis_button_facebook_follow"></a> <a class="addthis_button_twitter_follow"></a> <a class="addthis_button_linkedin_follow"></a> <a class="addthis_button_pinterest_follow"></a></div><p> </p><script src="//s7.addthis.com/js/300/addthis_widget.js#pubid=ra-52fbd23a7539ccda" type="text/javascript"></script><!-- AddThis Follow END --></div> </aside> </div> </div> </div> <div id="tm-bottom-a" class="tm-block-bottom-a uk-block uk-block-muted tm-block-fullwidth uk-block-large " > <div class="uk-container uk-container-center"> <section class="tm-bottom-a uk-grid uk-grid-divider" data-uk-grid-match="{target:'> div > .uk-panel'}" data-uk-grid-margin> <div class="uk-width-1-1"><div class="uk-panel"> <div id="wk-gridfdd" class="uk-grid-width-1-1 uk-grid-width-small-1-2 uk-grid-width-medium-1-5 uk-grid uk-grid-match uk-grid-small uk-text-center logos" data-uk-grid-match="{target:'> div > .uk-panel', row:true}" data-uk-grid-margin data-uk-scrollspy="{cls:'uk-animation-slide-bottom uk-invisible', target:'> div > .uk-panel', delay:300}"> <div> <div class="uk-panel uk-invisible"> <a class="uk-position-cover uk-position-z-index" href="/#services/rehabilitation" target="_blank" title="Rehabilitation"></a> <div class="uk-text-center uk-panel-teaser"><img src="/images/logos/rehabilitation.png" alt="Rehabilitation" width="300" height="165"></div> </div> </div> <div> <div class="uk-panel uk-invisible"> <div class="uk-text-center uk-panel-teaser"><img src="/images/logos/sportsfit.png" alt="SportsFit" width="300" height="165"></div> </div> </div> <div> <div class="uk-panel uk-invisible"> <a class="uk-position-cover uk-position-z-index" href="/#services/sports-medicine-athletic-training" target="_blank" title="Encore Sports Medicine"></a> <div class="uk-text-center uk-panel-teaser"><img src="/images/logos/sports-medicine.png" alt="Encore Sports Medicine" width="300" height="165"></div> </div> </div> <div> <div class="uk-panel uk-invisible"> <a class="uk-position-cover uk-position-z-index" href="/#services/workzone-industrial-rehab" target="_blank" title="Encore WorkZone"></a> <div class="uk-text-center uk-panel-teaser"><img src="/images/logos/workzone.png" alt="Encore WorkZone" width="300" height="165"></div> </div> </div> <div> <div class="uk-panel uk-invisible"> <a class="uk-position-cover uk-position-z-index" href="/#services/contract-services" target="_blank" title="Contract Services"></a> <div class="uk-text-center uk-panel-teaser"><img src="/images/logos/contract-services.png" alt="Contract Services" width="300" height="165"></div> </div> </div> </div> <script>(function($){ // get the images of the gallery and replace it by a canvas of the same size to fix the problem with overlapping images on load. $('img[width][height]:not(.uk-overlay-panel)', $('#wk-gridfdd')).each(function() { var $img = $(this); 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